As shown in Panel B, progressive accumulation of mutations or other heritable properties leads to clonal relationships. Letters denote a mutation or heritable mark. Colors represent distinct ...

We identified recurrent mutations in coding genes and defined the clonal architecture of each pair of samples from the myelodysplastic-syndrome stage and the secondary-AML stage, using the allele ...

Clonal dominance is a phenomenon that occurs when descendants (i.e., clones) of one or more founder cells in an organism contribute disproportionally to the system's final structure as the tissue ...

Clonal hematopoiesis is a condition that arises when a single clonal lineage of hematopoietic stem cells (HSC) expands and becomes the source of a substantial proportion of mature blood cells. The ...

Tumor-infiltrating clonal hematopoiesis is associated with worse outcomes in patients with cancer, new research suggests.

A recent study has uncovered a surprising new risk factor for heart disease called clonal hematopoiesis. This condition ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating ...

Clonal cytopenia of undetermined significance (CCUS) corresponds to a clinically more advanced condition defined as CHIP in the presence of one or more persistent and unexplained cytopenia that does ...

Changes in blood are detectable at age 50 and universal by 60, paving the way for spotting early signs of unhealthy aging.

As with standard speed Twist Clonal Genes, Twist Express Genes are NGS sequence-verified and one hundred percent accurate. Twist Express Genes can be cloned into catalog vectors or custom vectors ...