When pancreatic tissue becomes inflamed, it creates a favorable environment for cancer to develop and spread. In fact, researchers found that just one or two days after tissue damage, cells already ...

Cancer is very smart, in a way; it finds the easiest path forward ... Thus, targeting epigenetic factors that change the accessibility of the chromatin could help regulate stem cell lineage plasticity ...

therapy resistance and lethality of metastatic cancer is driven by dynamic and tenacious metastasis stem cells (MetScs). The Ganesh lab focuses on understanding the molecular mechanisms that underlie ...

Outside of colon cancer, the methylation process may also ... Pashos et al, H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium, Nature Cell Biology (2025).

Researchers from the University of Colorado Cancer Center have solved ... methylation process in regulating plasticity and regeneration in intestinal cells. The intestine has an enormous ability ...

Auron Therapeutics, a clinical-stage biotechnology company targeting cell-state plasticity to improve patient outcomes in oncology and inflammatory disease, today announced preclinical data in ...

Cancer stem cells, characterized with self-renewal, differentiation, heterogeneity, plasticity and tumorigenicity, are regulated by intrinsic factors such as signaling pathways, transcription ...