Pe'er said in a recent interview. "We call this ability for cells to run new programs 'plasticity.' So cancer doesn't ...

Cancer is very smart, in a way; it finds the easiest path forward ... Thus, targeting epigenetic factors that change the accessibility of the chromatin could help regulate stem cell lineage plasticity ...

Technological advancements over the past few decades have unraveled the diversity and adaptability of tumors, shedding light ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

The poster presented data from AUTX-703, a potent, selective and orally bioavailable heterobifunctional degrader of KAT2A/B, an AURIGIN-identified histone acetyltransferase driving small cell lung ...

Outside of colon cancer, the methylation process also may have implications for resistance to ... Reference: Pashos ARS, ...

Circadian rhythms are the daily fluctuations in physiological processes that govern cell cycles and timing of behaviors. Cancer hallmarks are the cellular properties that drive the perennial growth, ...

The Mark Foundation for Cancer Research convened more than 150 scientists from 13 states and seven countries at its 2025 Scientific Symposium in New York City on April 3, 2025. The event provided a ...

Auron will present data highlighting the activity of AUTX-703, its oral, potent and selective degrader targeting KAT2A/B in cell lines and patient derived organoid models (PDXO) of neuroendocrine ...

ORIC-944 is a potent, highly selective, orally bioavailable, allosteric inhibitor of PRC2 that demonstrates best-in-class drug properties, including potency, solubility, and pharmacokinetics, with ...