Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...

Gout attacks are caused by inflammation in joints that arises from reaction to crystals of urate. Gout, which is often associated with binge drinking or eating poorly, may be more genetically ...

Although it is less common, younger people can also develop gout, which tends to be more severe when they do. Gout occurs when urate, a substance in the body, builds up and forms needle-shaped ...

Gout develops from hyperuricemia—high urate levels in the body—which causes sharp crystals to build up in the joint. Medications and lifestyle changes can help reduce symptoms of gout in the ...

A new study finds that obesity significantly reduces the effectiveness of urate-lowering therapy in male gout patients, with ...

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...

Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below its saturating point (400 μmol/l). Time to crystal clearance relates to ...