Matrix metalloproteinases (MMPs) contribute to the breakdown of tissue structures such as the basement membrane, promoting tissue fibrosis. Here we developed an electrospun membrane ...

A new review published in Genes & Diseases highlights the transformative role of microRNAs (miRNAs) in regulating and potentially reversing adipose tissue fibrosis, a condition closely linked to ...

Image Caption: TGF-β/Smad signaling pathway and miRNA regulation in liver fibrosis. Tissue fibrosis intricately links with the TGF-β/Smad signaling pathway. Ultimately, the findings underscore ...

In a recently published article, "Hepatocyte-macrophage acetoacetate shuttle protects against tissue fibrosis," in Cell Metabolism, authors Peter Crawford, MD, PhD, Professor of Medicine and ...

Yale researchers have identified a possible driver of the persistent inflammation that causes irreversible lung damage in patients with cystic fibrosis, a genetic disorder that impairs breathing ...