S. aureus is a major source of superantigens 5. These toxins can activate up to 20% of all T cells in the body by binding the human leukocyte antigen (HLA) class II molecules on antigen-presenting ...

Superantigens could be behind several illnesses Date: November 29, 2010 Source: University of Gothenburg Summary: Superantigens, the toxins produced by staphylococcus bacteria, are more complex ...

Our immune system is fine-tuned to respond to a variety of different antigens, but some pathogens have found a way to hijack the immune system. Superantigens interfere with the adaptive immune system.

Our immune system is fine-tuned to respond to a variety of different antigens, but some pathogens have found a way to hijack the immune system. Superantigens interfere with the adaptive immune system.

According to the UI study, the culprits are superantigens -- toxins produced in large quantities by Staphylococcus aureus (staph) bacteria -- which disrupt the immune system, turning it from ...

Toxic shock syndrome is a life-threatening inflammatory response brought on by exposure to bacterial superantigens, which are toxins harbored and secreted by certain common bacteria, namely ...

Superantigens, the toxins produced by staphylococcus bacteria, are more complex than previously believed, reveals a team of researchers from the University of Gothenburg in an article published ...

Researchers used both animal models and human cells to demonstrate the hyper-responsiveness of MAIT cells to systemic exposure to bacterial superantigens. The team also demonstrated that as MAIT ...

Superantigens are proteins that hyper-stimulate immune responses. These proteins may trigger T cells via the crosslinking of T cell receptors (TCR) with MHC Class II molecules or even hyper ...

In the case of strep A infections, the bacterium secretes toxic proteins called superantigens that bind to HLAs. The superantigens seem to overstimulate the immune system and thereby prevent an ...

Schlievert had already shown which toxins, or “superantigens,” produced by staph bacteria can disrupt the immune system and cause a rare and potentially fatal illness called toxic shock ...