In this study, we report for the first time that Medicarpin (Med), a naturally occurring phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis. Combination of Med and TRAIL ...

特拉维夫大学的研究人员在Nature Nanotechnology上发表了Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to ...

Ozcan's team initially identified celastrol's effects several years ago, through a screen of more than 1,000 compounds. Ozcan later founded ERX Pharmaceuticals to take celastrol and other leptin ...

More information: Ali Vaziri-Gohar et al, Increased glucose availability sensitizes pancreatic cancer to chemotherapy, Nature Communications (2023). DOI: 10.1038/s41467-023-38921-8 ...

The effective targeting of RAS-mutant acute myeloid leukemia (AML) still remains a challenge; RAS mutations are tied to relapse to targeted therapy, such as resistance to FLT3 inhibitors due to the ...

The abstract, “SARS-Cov-2 Spike Protein Sensitizes Nociceptors and Evokes Nociceptive Behaviors” was presented during the “AADOCR Hatton: Junior” Poster Session that took place on Friday ...

Targeted anti-cancer therapies dramatically improve patient outcomes in EGFR-mutant lung adenocarcinomas, 1 but many tumors acquire resistance to these drugs over time. Because there are numerous ways ...