Rifapentine was shown to have greater bactericidal activity against Mycobacterium leprae than rifampin in murine models of leprosy, but data regarding its effectiveness in preventing leprosy are ...

Rifapentine-based regimens have potent antimycobacterial activity that may allow for a shorter course in patients with drug-susceptible pulmonary tuberculosis. In an open-label, phase 3 ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their ...

(HealthDay)—A four-month rifapentine-based regimen containing moxifloxacin is noninferior to a standard six-month regimen for treatment of tuberculosis, according to a study published in the May ...

Learn everything you need to know about Rifapentine-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it. Get up-to-date information on side effects, precautions ...

Type of Study Phase 2 clinical trial of TB treatment with pharmacokinetic and surrogate biomarker substudies; current trials being conducted \x96 TBTC Study 29; TBTC Study 29 PK Design Phase 2 ...

Review the side-effects of Rifapentine as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of ...

Co-administration of dolutegravir-based antiretroviral therapy and short course (12 weeks) of rifapentine/isoniazid (3HP) for people living with HIV needing preventative treatment for latent ...

Moreover, the trial showed that the antibiotic, rifapentine, was an even more effective form of what’s known as “post-exposure prophylaxis,” or PEP, than another antibiotic, rifampin ...

A single dose of rifapentine reduced the incidence of leprosy among household contacts of patients with the infectious disease, a cluster-randomized trial out of China found. In an intention-to ...

To identify an improved treatment regimen to shorten treatment duration for drug susceptible strains, efficacious against resistant strains that could overall reduce the incidence of TB worldwide.