Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...
However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...
1 First, the researchers generated stopless-ORF circular RNAs (socRNAs) that promoted continuous translation for extended periods of time. The researchers visualized translation, including ribosome ...
As they are being synthesized, these nascent proteins simultaneously attempt to fold while still associated with their parent ribosome, referred to as co-translational protein folding ...
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...
ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...
These rRNAs play a role in peptide bond formation and translocation. The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome ...
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