Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve ...

These results confirm the association of 1q21.1 rearrangements with a broad spectrum of phenotypes but also further dispel the notion that rare copy-number variants will necessarily follow the one ...

Scientists have uncovered a critical role for rapid DNA repair in maintaining genome stability. A new study reveals that ...

SAVANA uses a machine learning algorithm to identify cancer-specific structural variations and copy number aberrations in ...

Chromosomal rearrangements where large chunks of chromosomes are inverted, moved, deleted or duplicated, provide a possible source for such large-scale "macromutations." However, characterizing ...

A multicenter, randomized, controlled, pivotal trial of microbubble-enhanced transcranial focused ultrasound for patients with NSCLC brain metastases (LIMITLESS).

Chromosomal rearrangements where large chunks of chromosomes are inverted, moved, deleted or duplicated, provide a possible source for such large-scale "macromutations." However, characterizing ...

These findings highlight gene fusions as important diagnostic and therapeutic targets across cancer types and demonstrate that FFPE RNA can be used reliably for their detection, even for novel ...

We have used imatinib mesylate to treat four patients with chromosomal rearrangements involving PDGFRB. All had prompt responses, with normalization of the blood count, disappearance of ...

In a recent study posted to the bioRxiv* preprint server, researchers explored genomic rearrangements in monkeypox (MPX) virus (MPXV) genomes and investigated whether such rearrangements ...