RRV-transduced cells showed significant radiosensitization even after transient exposure to 5-FC. This was confirmed both in vitro by a clonogenic colony survival assay and in vivo by ...

Radiosensitization With Carboplatin for Patients With Unresectable Stage III Non–Small-Cell Lung Cancer: A Phase III Trial of the Cancer and Leukemia Group B and the Eastern Cooperative Oncology Group ...

It is typically only observed in solid tumors, whereas normal tissues tend to have sufficient amounts of oxygen from a radiosensitization point of view. The level of hypoxia that causes ...

However, optimal implementation of EGFR inhibitors as radiosensitizers depends, in part, on a better understanding of the mechanisms of radiosensitization. Preclinical studies provide important ...

In addition to a sonoporation-augmented delivery increase, multiple other cellular Modes of Action change the receive characteristics of cells, including one that enhances radiosensitization of tumors ...

This project aims to develop and characterize nano-scale phase change droplets < 200 nm from commercial ultrasound contrast agents and demonstrate their ability to enhance HCC tumor radiosensitization ...