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它们排列在核孔的渗透性通道上,允许中间丝(intermediate filament)的组装,并协助组装各种不被脂质膜包围的核斑点(nuclear puncta)和细胞质斑点 ...
模型在 puncta形成、内在无序区(IDR)预测等任务中超越基线模型,并能零样本预测耐药突变,为融合驱动型癌症的靶向治疗提供了新工具。 在儿童癌症和多种恶性肿瘤中,由染色体易位产生的融合癌蛋白(如EWSR1::FLI1、PAX3::FOXO1等)是关键的驱动因子。这些嵌合 ...
Axin-RFP forms cytoplasmic punctate structures, similar to endogenous axin puncta. Axin-RFP recruits β-catenin destruction complex proteins, including APC, β-catenin, glycogen synthase kinase-3 ...
[1] The upper lacrimal drainage system starts at the puncta, canaliculi, and the common internal puncta (opening of common canaliculus) and drains into the lacrimal sac. The lower lacrimal ...
Also known as the “lacrimal puncta (or points)”, they are tiny openings inside the edges of the top and bottom lids, and are located on the side closest to our nose. The Reddit user took to ...
I always plug the inferior puncta first because it is much easier for me. The upper puncta are more difficult to work with. Cliff Scott, OD, from New England College of Optometry, gave me a great ...
The holes, known as lacrimal puncta, actually drain fluid away from our eyes, taking tears down a channel to our nose where they can be reabsorbed, explaining why we get the sniffles when we have ...
These tiny openings are known as the puncta, and they allow excess tears to drain from the surface of the eye into the nose. This is why you sometimes get a runny nose when you cry. In addition to ...
As their name suggests, they can “plug” the puncta (tear ducts) in the eyes, which may help alleviate symptoms of dry eye. Usually, the puncta in your eyelids are responsible for creating ...