In this Perspectives article, we describe the role of prostanoids in bladder physiology, summarize the findings from animal model and human studies and discuss the clinical use of prostanoids in ...

10, 11 Disorders involving the biotransformation of arachidonic acid derivates (prostanoids) are also postulated to be an important factor in ED pathogenesis. 17 An imbalance between the ...

Patients who were receiving no other treatment for pulmonary arterial hypertension and patients who were receiving endothelin-receptor antagonists or (nonintravenous) prostanoids were eligible.

The drug given at 10 mg/day led to a 45% reduction (p<0.001) in a clinical primary end point that included death, initiation of IV or subcutaneous prostanoids, or worsening of PAH. The benefit was ...