In cycling tumour cells, the binary cyclin-dependent kinase Cdk4/cyclin D or Cdk2/cyclin E complex is inhibited by p21 following DNA damage to induce G1 cell-cycle arrest. However, it is not known ...

Nuclear pores are essential elements of all ... of the Nup Tpr in coordinating signal transduction pathways during cell proliferation and the dynamic organization of the nucleus.” ...

proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research. As the scientists continue to investigate the ...

Iran’s belligerence and its nuclear programme loom over the likes of Saudi Arabia and Turkey (see article). Proliferation is not a chain reaction, but it is contagious. Once the restraints start ...

A recent study published in the Cell Chemical Biology Journal described a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) that selectively kills cancer cells. PCNA is a ...

could someday help scientists better understand illicit nuclear explosions and curb nuclear proliferation. As a young seismologist in the 1960s, Lynn Sykes made crucial observations of earthquakes ...

Recent findings by the International Atomic Energy Agency (IAEA) that some non-nuclear-weapon States (NNWSs) party to the "Treaty on the Non-Proliferation of Nuclear Weapons" (NPT) had been able to ...

The U.S. government has continued to express concerns about China’s record concerning the proliferation of nuclear- and missile-related technologies to other countries, with more recent focus on ...

WASHINGTON, Jan 8 (Reuters) - The U.S. agency in charge of nuclear security is commissioning a study on the proliferation risks of a more-enriched uranium fuel that nuclear power developers want ...

Over the next decade, the spread and maturation of additive manufacturing could challenge major control mechanisms for inhibiting nuclear proliferation. At the same time, the cyber-physical nature of ...