Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and ...

After silently lurking for almost 50 years, a prion disease erupted in the brain of a woman in the US, triggering a rapid and ...

A study from Bochum describes a mammal-specific domain of the prion protein and offers new approaches for research into neurodegenerative diseases. Prion diseases are progressive and invariably ...

The deaths of two people and illness of one from a possible fatal and rare brain disease clustering in Oregon have public ...

This "mini prion" induces misfolding in normal tau, and its behavior is influenced by water structure around the protein, particularly by the P301L mutation. These findings may aid in developing ...

Misfolded, prion-like proteins drive the progression of tauopathies, a group of neurodegenerative diseases—including Alzheimer's disease—characterized by the abnormal accumulation of misfolded ...

An autopsy had revealed the cause to be prion disease, in which the prion protein, the normal function of which is unclear, changes form and spontaneously clumps together and causes the brain to die.

it is still unclear in what way misfolded proteins trigger cell death. A team headed by Professor Jörg Tatzelt, head of the Department of Biochemistry of Neurodegenerative Diseases at Ruhr University ...

An American woman passed away from Creutzfeldt-Jakob disease. She likely contracted it from contaminated growth hormone treatments as a child. The dis ...

To understand the importance of the prion protein in cancer biology, it is first necessary to understand the mechanism of action of glioblastoma. As Lopes explains, surgery and treatment with ...