What is a polybasic cleavage site? Proteolytic excision at polybasic cleavage sites is a post-translational modification phenomenon required for the maturation and activation of several precursor ...

As compared to other sarbecoviruses and mammalian coronaviruses (CoVs), SARS-CoV-2 is highly transmissible due to a functional polybasic FCS between the S1 and S2 subunits of its spike (S ...

A computer model showing the polybasic cleavage sites, located on the novel coronavirus' protein spike. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...