在生物医学研究的广阔领域中，实验动物模型的遗传工程发挥着关键作用，尤其是转基因小鼠，为基因功能的探索和人类疾病的模拟立下了汗马功劳。然而，小鼠模型与人类在生理和代谢功能上存在着较大差异，就像用一把不太合适的钥匙试图打开人类疾病的大门，很难精准地重现人类疾病的真实病理。 非人灵长类动物，作为人类的近亲，与人类在遗传上高度相似，成为了研究人类生物学和疾病的宝贵实验模型。食蟹猴（cynomolgus ...

Researchers successfully use a nonviral, piggyBac transposon system to introduce a transgene into cynomolgus monkeys.

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, ...

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease ...

Genetic engineering in non-human primates has long been limited by the need for virus-based gene delivery methods. Recently, ...

To overcome these challenges, the research team sought an alternative to using viruses to carry transgenes, instead opting for a nonviral piggyBac transposon system. Transposons, which are sequences ...