The risk in sixteen (38%) of these variants was for diseases other than the pharmacogenetic indication (Table 1). Seven variants (17%) were associated with risk for at least two different diseases.

This suggests that pharmacogenetic effects may need to be considered when CRF receptor 1 (CRF 1) antagonists are developed for the treatment of alcoholism. GABAergic and serotonergic transmission ...

Data supporting the clinical utility of routine use of pharmacogenetic testing for both these drugs are evolving. 8–10 Genomewide association studies have confirmed the identity of genetic ...

Fig 1. Graphical demonstration that overall survival was not different between patients with blood samples for pharmacogenetic study and patients without blood sampling. Blue line, patients who had no ...

Genetic variability among patients plays an important role in determining the dose of warfarin that should be used when oral anticoagulation is initiated, but practical methods of using genetic ...

Pharmacogenetic testing was associated with nearly a two-fold (89%) increase in remission rates compared to treatment as usual in a Centre for Addiction and Mental Health- (CAMH-)led clinical ...

A growing number of companies are offering pharmacogenetic testing kits. Customers swab their cheek, mail the cells to a lab and receive a customized list of medications that will or will not work ...

And they found that in more than one in five occasions (21.1 per cent) there was the potential for a doctor or pharmacist to take action under international pharmacogenetic guidelines. If this ...

“That was really the crux of the study,” Oslin said. “Does the pharmacogenetic test help you choose the medicine that you want to use with this particular patient?” The study found a ...

The large individual variability for ovarian cancer patients in both outcome and toxicity risk from chemotherapy makes the identification of pharmacogenetic markers that can be used to screen patients ...

In addition, the contract includes pharmacogenetic testing. Pharmacogenetics uses genomic information to determine how patients will respond to certain medications--an important component of ...

UC San Francisco will be the first hospital in California, and one of only a few nationwide, to offer pharmacogenetic testing. The test will provide critical clues about a patient’s unique genetic ...