本研究针对骨肉瘤(OS)高复发率与不良预后的临床难题，首次揭示传统中药Cyclocarya paliurus主要活性成分阿江榄仁酸(AA)通过靶向Wnt3a信号轴调控肿瘤相关巨噬细胞(TAMs)极化，抑制M2型巨噬细胞分化并促进促炎性M1表型转化，从而显著抑制OS细胞增殖、迁移和侵袭。

One of the most intriguing medicinal plants is Cyclocarya paliurus, which has been used as the drug formulation in traditional Chinese medicine as well as the ingredient in healthy foods and ...

One of the most intriguing medicinal plants is Cyclocarya paliurus, which has been used as a drug formulation in traditional Chinese medicine as well as the ingredient in healthy foods and dietary ...