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这些研究结果有可能促成骨质疏松症新疗法。相关论文发表在《细胞代谢》(Cell Metabolism)杂志上。 Orexins是神经细胞利用来进行相互通讯的一种蛋白。自15多年前德克萨斯大学西南医学中心的研究人员发现Orexins以来,它们被证实调控了许多的行为,包括觉醒 ...
生物通报道:研究发作性睡病(narcolepsy,一种睡眠疾病),为治疗失眠提供线索。1/10的美国人被慢性失眠困扰,使美国的 ...
In addition, orexins are essential regulators of REM sleep, the sleep stage characterized by vivid dreams and paralysis of nearly all muscles. Figure 1: Among their many functions, the orexin ...
Orexins are neurotransmitters, which are chemicals in your brain that send messages from one neuron (a nerve cell) to another. When you’re awake, those neurons send out orexins. The orexins then ...
These results suggest that (Fig. 8) acute restraint stress activates orexin neurons in the LH, which send projections to the VTA, releasing orexins that activate postsynaptic OX1Rs on VTA ...
Enter orexins. A neuropeptide that’s secreted by neurons in the hypothalamus, orexins play a starring role in a host of vital functions including mood, eating behavior, energy, cognition and sleep.
The investigational drug works on receptors in a region of the brain that’s key for allowing us to fall into slumber: the lateral hypothalamus, where molecules called orexins are released ...
Orexins are rather unique in that they allow one to eat more and lose more at the same time, explained Devanjan Sikder of the Sanford-Burnham Research Institute. "It is a couch potato's dream." ...
The new sleep aids block the activity of brain peptides called orexins. These tiny proteins keep us wide awake and attentive during the day, and they also govern some stimulating effects of ...
Orexins are one of the substances in the brain that cause you to feel more awake. Quviviq is known as an “orexin receptor antagonist.” It blocks the wakeful effect of orexins, which leads to ...
The treatment belongs to a new class of medications called dual orexin receptor antagonists that work by blocking chemical messengers called orexins, which are responsible for keeping people awake.