Understanding the frequency of oncogenic variants in specific populations helps elucidate carcinogenesis and risk factors, with somatic variants often serving as treatment markers. Data regarding the ...

Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...

The new technique, called STRACK, allows monitoring of the evolution of each cell before and after acquiring oncogenic mutations. Myeloid leukaemias are among the most aggressive blood cancers and ...

DelveInsight's "VITRAKVI Market Size, Forecast, and Market Insight Report" highlights the details around VITRAKVI, a TRK, ...

CAMBRIDGE, Mass., March 06, 2025 (GLOBE NEWSWIRE) -- Black Diamond Therapeutics, Inc. (Nasdaq: BDTX), a clinical-stage oncology company developing MasterKey therapies that target families of oncogenic ...

Previously we found that activation of ERK output is dependent upon the mechanisms by which oncogenic mutants evade ERK-dependent feedback regulation. The loss of feedback regulation not only drives ...