Here we focus on the transformation assay, which scientists first used to identify oncogenes and tumor suppressors and study their affect on cell cycle progression. Even more important will be ...
Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to ...
Tumor suppressors act to maintain checkpoints (arrows) whereas oncogenes allow for checkpoints to be overcome (stop lines) (Adapted from Kopnin 2000). How is a normal cell transformed into a ...
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