2023年12月5日,华中科技大学生命科学与技术学院朱斌教授团队在国际核酸领域顶级期刊《Nucleic Acids Research》发表题为“ The nuclease-associated short prokaryotic Argonaute system nonspecifically degrades DNA upon activation by target recognition ...

来自Milwaukee的消息，威斯康新医学院、Sangamo Biosciences、Sigma-Aldrich、Open Monoclonal Technology以及INSERM公司联合宣布使用zinc finger nuclease (ZFN)技术成功培育出首只靶基因敲除大鼠 在7月24日出版的《Science》杂志上，研究人员描述使用ZFN技术来培育永久可遗传的基因突变 ...

GMP Salt Active GENIUS ™ Nuclease is developed using ACROBiosystems' unique enzyme AI evolution platform, based on wild-type Serratia marcescens endonuclease. It maintains high specific activity ...

Aldevron, a leading contract development and manufacturing organization serving the biotech industry, announces the release of GMP SpyFi Cas9 Nuclease for clinical and commercial applications. SpyFi ...

AsCas12a Ultra is an advanced CRISPR nuclease with significant advantages in basic research and in the production of gene edited cell medicines. Learning Objectives: 1. Identify the engineered ...

The team observed a 4.4-fold increase in the editing efficiency of this modified nuclease, surpassing most of the commonly used RNA-guided endonucleases, including CjCas9. They called this variant ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on an initial demonstration of its success in ...

How would that work? In the April 4 Nature Neuroscience, scientists led by Thomas Massey and Lesley Jones at Cardiff University, Wales, U.K., report that certain rare coding mutations in ...

Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform gene editing in non-liver tissues, including skeletal muscle ...

Safety is the first important thing to consider when advancing a nuclease. We compare our off-target screens using industry-standard systems to look for any off-target effect genome-wide.