Research in our lab is focussed on identifying the signalling pathways and molecules controlling secretion from neurones and mast cells, with a special interest in voltage-gated (CaV), ligand-gated ...

Kineta is partnering with Genentech–Roche in an on-going research, option and licensing agreement to develop an antagonist of the α9/α10 nicotinic acetylcholine receptor (nAChR) for treatment ...

and that the proangiogenic effects of nicotine are mediated by non-neuronal nAChR and might involve the elaboration of nitric oxide, prostacyclin and VEGF. HUVECs were grown in M199 (10% FBS ...