Traditionally, pooled microsomes have consisted of a wide range of averaged enzyme activity levels in an attempt to address a variety of different assay requirements with a single product.

Includes seven cryopreserved human liver microsomes (HLM) pools that are each pretreated with a mechanistic-based inhibitor targeting a single CYP enzyme. This chemical inactivation is mechanism ...

To characterize the metabolism of nuciferine by P450 enzymes and uridine diphosphate glucuronosyltransferase (UGT) in liver microsomes from humans and several other animals including rats ...

A total of eight metabolites (M1-M8) were identified, and three major metabolic pathways were found: demethylation (M1), dehydrogenation (M2, M3, M7), and oxidation (M4, M5, M6, M8). The study was ...

A total of eight metabolites (M1-M8) were identified, and three major metabolic pathways were found: demethylation (M1), dehydrogenation (M2, M3, M7), and oxidation (M4, M5, M6, M8).