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Newly discovered mechanism regulates microglial characteristics in early brain developmentThey found that small fragments called micronuclei produced by neuronal nuclei are released into the extracellular space during the early establishment of the postnatal brain. They also found that ...
Various nuclear shape abnormalities such as micronuclei and nuclear blebs both close to the main nucleus. Nuclear shape abnormalities can lead to a severe impact on genomic DNA integrity.
In this study, detailed observations of the embryonic mouse brain revealed that small nuclear fragments called micronuclei are produced and released into the extracellular space as neurons migrate ...
These errors result in the formation of micronuclei, which are small structures separate from the main nucleus that often contain lagging chromosomes or fragments. Unlike the main nucleus ...
Nuclear envelope ruptures are rapidly repaired in the nucleus, but persist at aberrant, nuclear compartments, such as micronuclei and DNA bridges, that form around mis-segregated chromosomes.
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