Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

MicroRNA (miRNA) was initially discovered in Caenorhabditis elegans by Victor Ambros' laboratory in 1993 while studying the gene lin-14. At the same time, Gary Ravkun identified the first miRNA ...

A study of a recently discovered microRNA gene reveals that its function is to regulate the secretion of insulin in the pancreas. The findings, which for the first time define a biological ...

The microRNA produced by the lin-4 gene, which inhibited lin-14, was named lin-4 microRNA. The two scientists performed further experiments, ...

A microRNA gene codes for a big of RNA that can stick to a part of a messenger RNA, turning off protein assembly. 5W Infographics [/] You Might Also Like. The Stuff of Genes.

Typically the miRNA comes from a longer molecule, perhaps around 70 nucleotides long, known as pre-­miRNA. This molecule is seized by an enzyme called Dicer, which chops it into smaller fragments.

The longer form of the RNA produced from a microRNA gene acts as a precursor. It's able to fold over and base-pair with itself, forming a structure called a hairpin.

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed ...

The 2024 Nobel Prize in Physiology or Medicine was jointly awarded to Victor R. Ambros, PhD, and Gary Ruvkun, PhD, for the discovery of microRNA and its role in gene regulation.The Nobel Assembly ...

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled ...