磷脂酰肌醇 3-激酶（PI3K）/蛋白激酶 B（AKT）/哺乳动物雷帕霉素靶蛋白（mTOR）通路是细胞内重要的信号传导通路之一，该通路的异常激活在多种疾病特别是恶性肿瘤中发挥着关键作用。近年来，靶向 PI3K/AKT/mTOR ...

Redox Biology: Sty1/MAPK-mTOR信号轴调节线粒体的形态和功能 来源：生物谷原创 2024-05-26 12:47 在本研究中，研究者使用裂解酵母Pombe作为模式生物来研究 ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Davis, Jack. (2020, March 09). What is the mTOR Signaling Pathway?.

A new signaling pathway for mTor-dependent cell growth. Forschungsverbund Berlin. Journal Nature Cell Biology DOI 10.1038/s41556-019-0377-3 ...

Fig 1. PI3K/AKT/mTOR signaling pathway showing interacting activation and regulatory feedback loops. Adapted from Hoeffer and Klann. 35 Mammalian target of rapamycin (mTOR) is a serine-threonine ...

Forschungsverbund Berlin. (2019, August 27). A new signaling pathway for mTor-dependent cell growth. ScienceDaily. Retrieved May 14, 2025 from www.sciencedaily.com / releases / 2019 / 08 ...

Background: Gallbladder cancer (GBC) is a highly malignant tumor usually diagnosed at advanced stages and characterized by a poor prognosis. Effective therapeutic strategies are urgently needed to ...

A longtime interest of the lab is the signaling pathway anchored by the mTOR kinase, which David discovered when he was an M.D./Ph.D. student at Johns Hopkins Medical School.