结果表明 SAHA 可通过抑制 mTOR 和 NF-κB 信号通路减轻皮肤光老化，为防治皮肤光老化提供新方向。 在阳光的照耀下，皮肤作为人体最大的器官，却时刻面临着紫外线的威胁。近年来，臭氧层不断损耗，紫外线 B（UVB）辐射强度急剧增加。过量的 UVB 辐射可导致皮肤 ...

A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...

The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways ... within the RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. Furthermore, the study explores the ...

Innovations in therapeutic strategies, coupled with a deeper understanding of breast cancer biology, will be essential for advancing personalized ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are ... are selectively dependent for growth on the ...