Preclinical data has showing compelling findings for HT-KIT among patients with rare and aggressive KIT-driven cancers, ...

转录终止（transcription termination）是指RNA聚合酶（RNA polymerase，RNAP）停止RNA延伸、释放RNA并从DNA解离的过程。正确的转录终止对mRNA的稳定性和RNA聚合 ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

The team needed a way to get the transcription factor into liver cells, so they turned to mRNA technology. Used in some of the Covid-19 vaccines, mRNA is a molecule that carries instructions for ...

When developing mRNA therapeutics, capping technology plays a crucial role in determining the stability, translation efficiency and immunogenicity of synthetic mRNAs. Advancements in ...

K nowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

These two transcription factors are delivered to the heart cells using synthetic mRNA. This technology, widely used in COVID-19 vaccines, works by instructing cell ribosomes to produce certain ...

US drugmaker Moderna has signed a deal to make mRNA medicines in China as part of its first major investment in the country, despite escalating trade and political tension between Washington and ...

A team led by research hospital Massachusetts Eye and Ear and German biotech CureVac has designed an mRNA therapy that delivered a therapeutic gene transcript to the eyes of rabbits with the ...

Sponsor Message Now, more than 40 grants related to vaccine hesitancy have been cancelled, and there are mounting concerns that research on mRNA vaccines could be on the chopping block next.