As dysfunctional lysosomal activity is linked to inflammation, Harvey et al. focus on nuclear receptor coactivator 7 (NCOA7), which binds to V-ATPases to modulate lysosomal function and is up ...

Liu Cuihua's group at the Institute of Microbiology of the Chinese Academy of Sciences revealed a pathogenic mechanism by which Mtb manipulates host lysosomal protease activity-dependent ...

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by ...