While it is known that chimeric fusion proteins often drive constitutive kinase signaling in leukemic cells, few data exist revealing how these proteins perturb lymphoid development and contribute ...

Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now, ...

Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas. However, not all lymphoid lesions at present can ...

Researchers from Osaka University found that plasma cells expressing high levels of the protein integrin β7 and the ...

GvL mainly occurs in lymphoid tissues, such as bone marrow and lymph nodes, where the malignant hematological cells reside. GvHD, by contrast, occurs throughout the body after donor T cells become ...

AtLP are conditions in which it is not possible to differentiate between the benign and the malignant nature of a given lymphoid infiltrate. The descriptive term AtLP may be used as an interim ...

A recent Nature Immunology study explores the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection. Study: Temporal Profiling of ...

Chemotherapy remains the primary treatment approach for paediatric cancer patients, with nearly 73% of cases undergoing this ...

Bioheng Therapeutics US LLC ("Bioheng"), a clinical-stage biotech company dedicated to developing innovative universal CAR-T cell therapies, today announced that the U.S. Food and Drug Administration ...

Anthony Stein, MD, assessed total marrow and lymphoid irradiation with post-transplant cyclophosphamide in patients with ...

Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now ...