Coprimary outcomes were laxation (defecation) within 4 hours after the first dose of the study drug and laxation within 4 hours after two or more of the first four doses. Patients who completed ...

and advanced medical illness were randomly assigned to receive a single 0.15-mg/kg or 0.3-mg/kg dose of methylnaltrexone or placebo subcutaneously (s.c.). [15] Laxation within 4 hours was the ...

Patient perceptions of palliative care in the process of allogeneic hematopoietic cell transplantation.