Treating chronic inflammatory diseases with JAK inhibitors
Janus kinase (JAK) inhibitors are an important treatment option for people with chronic inflammatory diseases such as ...
ALZFORUM3d
Pretty in PINK1, Cryo-EM Reveals How Kinase Anchors to Mitochondria
This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...
Computational model enhances protein kinase target prediction for therapies
Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and ...
Avidity Biosciences announces del-zota topline data from EXPLORE44 trial
Avidity Biosciences (RNA) announced del-zota topline data from the Phase 1/2 EXPLORE44 trial in people living with Duchenne muscular dystrophy ...
Healio12h
Filgotinib well-tolerated, efficacious for up to 8 years in rheumatoid arthritis
Filgotinib, a Janus Kinase 1 inhibitor, remains well-tolerated for up to 8 years with consistent efficacy in patients with ...
Nurix Announces U.S. FDA Orphan Drug Designation Granted to Bexobrutideg (NX-5948) for the Treatment of Waldenström Macroglobulinemia
Orphan Drug Designation follows positive Phase 1 data presented at the 12th International Workshop on Waldenström MacroglobulinemiaFirst-in-class ...
Dual WEE1/YES1 Kinase Inhibitor MRANK-106 Secures FDA IND Clearance, Positioning MindRank in First-in-Class Oncology Pipeline
Powered Presicion Drug Design HANGZHOU, China and LONDON, March 07, 2025 (GLOBE NEWSWIRE) -- MindRank, a clinical stage ...
Healio8h
Deucravacitinib improves cutaneous lupus erythematosus activity
Twice-daily deucravacitinib 3 mg and 6 mg significantly improved cutaneous lupus erythematosus activity by week 16, according ...
Protein accidentally lassos itself, helping explain unusual refolding behavior
A new study has described a potential mechanism that could help explain why some proteins refold in a different pattern than ...
Knowridge Science Report2d
Compound in oranges may reduce obesity, heart disease risk
A recent study from Western University has found that a natural compound found in sweet oranges and tangerines, called ...
Janus Kinase (JAK) Inhibitor Pipeline Market Insights Report 2025: Comprehensive Review of 50+ Companies and Respective 55+ Drugs
The "Janus Kinase (JAK) Inhibitor - Pipeline Insight, 2025" drug pipelines has been added to ResearchAndMarkets.com's offering.The "Janus Kinase (JAK) Inhibitor- Pipeline Insight, 2025" report ...