Mast cells, which are abundant in the airways of asthmatic individuals, act as first responders to viral infections by ...

IL-23, or IL-17 reduced serious infections, while tofacitinib increased infection risk, according to one study.

T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

During this mission, the team will grow Janus base nanotubes that carry interleukin-12. Interleukin-12 is a protein already ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

Interleukin 2 (IL-2) is the only systemic treatment currently available that is capable of curing patients with metastatic renal cell cancer (RCC). The first indications that IL-2 could mediate ...

Low dose interleukin 2 is being tested as an immunomodulatory approach in neurodegenerative diseases. It increases the number and activity of regulatory T cells (Tregs) that suppress inflammation. At ...

When interleukin-12 is added to the cell culture, it leads to a significant reduction in nerve fibers (pink) and oligodendrocytes, and thus to a decline in myelin (white).

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

Adults and adolescents treated with icotrokinra experienced improvements in their moderate to severe plaque psoriasis, ...