Tolerance is characterized by a progressive lack of response to morphine that can be overcome by increasing the dose, whereas hyperalgesia is a sensitization process in which opioids ...

Hyperalgesia is a condition where a person has an increased sensitivity and extreme response to pain. What may not hurt most people can cause severe pain in a person with hyperalgesia. Although ...

Hyperalgesia is when you have extreme sensitivity to pain. If you have this condition, your body overreacts to painful stimuli, making you feel increased pain. You can develop hyperalgesia if you ...

Hyperalgesia is an enhanced pain response. It can result from either injury to part of the body or from use of opioid painkillers. When a person becomes more sensitive to pain as a result of ...

That is when American scientists showed that rats exhibited increased sensitivity to pain after exposure to morphine, a phenomenon that became known as opioid-induced hyperalgesia. By the 1990s ...

Silverman, MD. Concerns about hyperalgesia as opioid overuse in general faces intense public and regulatory scrutiny were evident from the overflowing crowd spilling out into a hallway at the ...

Researchers at the University of Alabama at Birmingham and Baylor College of Medicine, Houston, Texas, now have shown that blocking the activity of an enzyme called Tiam1 in certain spinal neurons ...

In previous behavioral research studies, Ahmed's laboratory demonstrated significant reversal of thermal hyperalgesia (heightened sensitivity to heat or thermal stimuli) and mechanical allodynia ...

Feeling increased pain or being hypersensitive to mild pain is called hyperalgesia. Allodynia is different from hyperalgesia, although a person may have both. In allodynia, a person can feel pain ...

Efficacy and tolerability of oxycodone for oxaliplatin-induced peripheral neuropathy and the extension of folfox therapy in colorectal cancer patients. This is an ASCO Meeting Abstract from the 2014 ...

Allodynia vs. hyperalgesia Unlike allodynia, which causes you to feel pain when you shouldn't, hyperalgesia heightens the amount of pain you feel in a situation when you normally would.