28 There is a direct interaction of the hydroxamic moiety of SAHA with the active zinc site of the catalytic pocket of HDAC (Figure 1). This interaction appears to be a prerequisite for optimal ...

Phase II study of vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in patients with advanced transitional cell urothelial cancer (TCC) after platinum-based therapy—California Cancer ...

A total of 39 patients with hematologic malignancy were enrolled (14 on IV SAHA and 25 on oral SAHA), of whom 35 were treated. The spectrum of diseases included patients with diffuse large B-cell ...

The scientists described the cells in “Hydroxamic acid preadsorption raises efficiency of cosensitized solar cells,” which was recently published in Nature. In an accompanying press release ...