资讯

针对绝经后骨质疏松问题,研究发现山柰酚通过hormesis效应双向调节成骨细胞(osteoblast)与破骨细胞(osteoclast)活性。低剂量(10-8-10-6 M)显著促进骨形成标记物ALP表达,而高剂量则抑制破骨细胞分化关键因子NF-κB活化。 Discussion部分 ...
这篇综述首次全面评估了黄酮醇漆黄素(Fisetin)诱导 hormesis 剂量反应的能力。研究表明,它能在细胞和动物模型中产生 hormesis 反应,对多个潜在治疗和公共健康相关指标产生影响,如延缓衰老、发挥神经保护作用等,值得深入探究。
此外,正是因为高压氧形成的激效效应(Hormesis),少量活性氧可唤醒机体内在抗压、抗氧化基因的表达,提高细胞清除自由基的能力,改善细胞 ...
Hormesis, the biological and toxicological concept that small quantities have opposite effects from large quantities, is reviewed with emphasis on its relevance to nutrition. Hormetic and other ...
Hormesis is set in motion at the other end of the thermometer, too, as with cold plunges and cryotherapy. Though these painful stressors are promising, more studies are needed.
Hormesis explains why exercise, nutrition, mental study, and even many medicines can be either healthful or harmful. If the world really had a supervillain, it would have to be stress.
Hormesis is about strength through adversity and resilience through harmful influences - and permeates our entire lives. Molecular biologist Nicklas Brendborg wanted to know the good side of ...