Histones are basic proteins, and their positive charges allow them to associate with DNA, which is negatively charged. Some histones function as spools for the thread-like DNA to wrap around.

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Histones, as linchpins of the apparatus for gene regulation, play a role in almost every function of eukaryotic cells. “In order to get complex, you have to have genome complexity, ...

The histones that we carry in our eukaryotic cells descend from similar but simpler proteins in a class of ancient one-celled organisms called archaea, which existed during that oxygen jump.

"Histones are proteins around which our DNA is wrapped and which thus serve to package the genetic material," says corresponding author Dr. Till Bartke, ...

Histones without DNA are like an instruction manual without words, so these experiments, led by research associate Christian Zierhut, focused on the two together, ...

H uman cells manage to store approximately two meters of DNA in a nucleus one-tenth the width of a human hair. This feat relies on a family of proteins known as histones, which serve as spools around ...

This valuable study identifies asymmetric dimethylarginine (ADMA) histones as potential determinants of the initial genomic binding of Rhino, a Drosophila-specific chromatin protein essential for ...

Histones are proteins that are used to organize and compact DNA. Some giant viruses called Marseilleviridae, which infect amoebas, have also been found to use histones; they wind their DNA around ...

Histone chaperone RbAp48 interacts with histones H3–H4 and delivers them to a second histone chaperone, ASF1, to be assembled into new nucleosomes. These interactions are now investigated ...

The paper Z. Li et al., “Lipid droplets control the maternal histone supply of Drosophila embryos,” Curr Biol, 22: 2104-13, 2012. The finding Excess free-floating histones are toxic to cells. Yet ...