The histone tag, characterized by lysine 8 acetylation on histone H4, identifies a significant departure from the histone ...

The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...

In a preprint uploaded to bioRxiv this January that has yet to undergo peer review, the team describes hundreds of potential histone proteins in bacteria, including one that they predict interacts ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

Scientists have discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

New research has uncovered a mechanism by which brain cancer cells reprogram immune cells from fighting cancer to enabling tumor growth.

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...

EZH2, a core component of the Polycomb Repressive Complex 2 (PRC2), plays a fundamental role in silencing tumor suppressor genes through histone methylation. Its overexpression has been implicated ...