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为解决食品工业中蛋白质颗粒作为界面稳定剂和生物活性分子载体的应用瓶颈,研究人员通过超小角/小角X射线散射(USAXS/SAXS ...
Celiac disease (CD) is driven by a chronic inflammatory T-cell response against the dietary protein gliadin, which results in small intestinal damage in genetically predisposed individuals.
Immunologist Tobias Freitag co-developed and tested nanoparticles containing gliadin for the immunomodulatory treatment of celiac disease in Professor Seppo Meri's research group at the University ...
We have proteases for it. We can break it down. We just can’t break it down completely: one of the pieces, named gliadin, does not get broken. This is not improper digestion, that’s just how ...
Gliadin is absorbed into the lamina propria and presented in conjunction with HLA-DQ2 or DQ8 cell-surface antigens by antigen-presenting cells, probably dendritic cells, to sensitized T cells ...
Gluten is digested by luminal and brush-border enzymes into amino acids and peptides. The gliadin peptides induce changes in the epithelium through the innate immune system and, in the lamina ...
The mice were reared on a gluten-free diet and then challenged with a portion of one of the gluten proteins called gliadin—a protein known to elicit a T cell response. (Gliadin is the half of ...
Immunologist Tobias Freitag co-developed and tested nanoparticles containing gliadin for the immunomodulatory treatment of celiac disease in Professor Seppo Meri's research group at the University ...
Immunologists developed and tested nanoparticles containing gliadin for the immunomodulatory treatment of celiac disease. Celiac disease affects 0.3-2.4% of people in most countries world-wide ...
Patients and methods: Enzyme-linked immunosorbent assay was applied for detection of serum immunoglobulin (Ig) A anti-gliadin antibodies at a concentration equal to or above 30 U and anti-F-actin ...
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