6月24日Cell杂志的报道“The primitive endoderm supports lineage plasticity to enable regulative development”，发现单独的PrE细胞就足以再生出完整的囊胚，并继续植入 ...

Gastrulation leads to three germ layers—ectoderm, mesoderm and endoderm—that are separated by two basement membranes. In the mouse embryo, the emergent gut endoderm results from the ...

Here we show that pancreatic endoderm derived from human embryonic stem (hES) cells efficiently generates glucose-responsive endocrine cells after implantation into mice. Upon glucose stimulation ...

We are interested in how cells become specialized, and how they collaborate at the population level to collectively build organs. Our focus is on the endoderm, the progenitor tissue that gives rise to ...

We are looking at cells in the mouse embryo called the primitive endoderm, also known as the hypoblast. We found these cells were unique and could generate an embryo on their own. This is ...

Laminin 521 (Cat. No. GMP-LA5H24) successfully maintained rapid expansion of human iPSCs, enabling cell passaging after just ...

Viotti M, Foley AC, Hadjantonakis AK. (2014) Gutsy moves in mice: cellular and molecular dynamics of endoderm morphogenesis. Philos Trans R Soc Lond B Biol Sci;369(1657). doi: 10.1098/rstb.2013.0547.

After fusing with a sperm, an egg develops into an early embryo called a blastocyst. It consists of dozens of cells of just three types: epiblast cells (forming the embryo), trophoblast cells (forming ...

The safety, tolerability, and efficacy of the implants, which consisted of pancreatic endoderm cells derived from human pluripotent stem cells (PSCs), were tested in 26 patients. While the insulin ...

Cellular Dynamics International (CDI) is licensing patented definitive endoderm differentiation technology from ViaCyte, a stem cell company focused on diabetes therapy. CDI will apply this ...

Physiologically, SOX17 influences the formation of the gut endoderm and the vascular system and has roles in endometrial receptivity and embryo implantation. 2 Using various animal models and gene ...