In the early limb bud, dorsal and ventral ectoderm converge to form the apical ectodermal ridge (AER), although the underlying mechanisms are unclear. By live imaging mouse embryos, we show that ...

Research conducted by Dr. Shota Nakanoh in a collaboration between Dr. Teresa Rayon's lab at the Institute and Professor Ludovic Vallier's lab at the Wellcome-MRC Cambridge Stem Cell Institute has ...

This disk splits into three distinct layers, the ectoderm, mesoderm, and endoderm. Following differentiation, the mesoderm forms a temporary backbone known as the notochord, this activity releases ...

Bioscientists develop a method to observe patterns of early embryonic development, during which ectodermal cells diverge toward their fates as skin, organs and the nervous system. During embryonic ...

Collaborative work has developed a cell culture system that differentiates human pluripotent stem cells to amniotic ectoderm and surface ectoderm based on cell density. Research conducted by Dr ...

At the very beginning of embryogenesis, 3 germ layers develop; the ectoderm, mesoderm, and endoderm. The ectoderm gives rise to the brain and skin (epidermis) and lies on top of the developing ...

Abstract 446, under the session ‘Experimental and Molecular Therapeutics’, showed that embryonic ectoderm development protein (EED) inhibitor APG-5918 exhibits potent anti-tumour activity and ...

Circulating tumor DNA (ctDNA) determinants of improved outcomes in patients (pts) with advanced solid tumors receiving the ataxia telangiectasia and Rad3-related inhibitor (ATRi), RP-3500, in the ...

The ectoderm or the outermost layer of the human embryo contributes to the formation of the teeth, hair, nails, lens and retina of the eye, and sweat glands. The development of these structures ...