Sulfonamides inhibit bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with aminobenzoic acid through competitive inhibition of the enzyme dihydropteroate ...

Sulfonamides, or “sulfa drugs,” are a group of medicines used to treat bacterial infections. They come in different formulations and may be taken as an oral, topical, vaginal, or ophthalmic ...

At approximately the same time, a second unpublished prediction was made of a gene that encodes an Archaeal homolog of dihydropteroate synthase (DHPS), a folate biosynthetic enzyme. Here ...