Patients with autosomal dominant vibratory urticaria have localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased ...

Mast cell degranulation produces inflammation, recruiting other immune cells such as monocytes and neutrophils, and T lymphocytes. These cells also affect the vascular tone and permeability ...

The infant had also been treated with inhibitors of mast-cell degranulation (cromolyn), of histamine H 1 and H 2 receptors (hydroxyzine and ranitidine, respectively), and of the cysteinyl ...

immunoglobulin E (IgE) antibodies, which are immune system proteins mast cell degranulation, which is the release of chemicals from specialized immune cells IgE-mediated reactions occur when ...

At the ongoing AAAAI meeting in San Antonio, researchers from Escient Pharmaceuticals Inc. presented preclinical data for the Mas-related G-protein coupled receptor X2 (MRGPRX2) antagonist EP-262, ...

When that person encounters the allergen again, the antibodies cause degranulation of the mast cell, releasing histamines that induce inflammation, i.e. an allergic reaction. Dr. Corinna Bowser, a ...