To examine the former possibility, cells were treated with 3′-deoxyadenosine in the absence or presence of proteasome inhibitor MG132 or lysosome inhibitor chloroquine. Western blot analysis ...

High-Dose Therapy and Autologous Stem-Cell Transplantation in Waldenström Macroglobulinemia: The Lymphoma Working Party of the European Group for Blood and Marrow Transplantation From December 2003 to ...

August 24, 2007 — The US Food and Drug Administration (FDA) has granted orphan drug designation for nitroimidazole PA-824 for the treatment of tuberculosis, 3'-deoxyadenosine for the treatment ...

Cell survival depends on having a plentiful and balanced pool of the four chemical building blocks that make up DNA -- the deoxyribonucleosides deoxyadenosine, deoxyguanosine, deoxycytidine ...