The metastatic incidence of retroperitoneal dedifferentiated liposarcoma is comparatively lower than other pleomorphic sarcomas, varying widely from 1 to 18%. Low-grade dedifferentiation ...

Imaging Modality and Frequency in Surveillance of Stage I Seminoma Testicular Cancer: Results From a Randomized, Phase III, Noninferiority Trial (TRISST) SEAL was a phase II-III, multicenter, ...

Molecular-genetic characteristics of soft tissue sarcomas associated with the development of chemotherapy resistance. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This ...

Dedifferentiated liposarcoma is a fast-growing and more aggressive type of soft tissue sarcoma that originates as a well-differentiated sarcoma and has a typical diagnosis age of 40 to 60 years.

The trial, evaluating the efficacy, safety, and tolerability of milademetan in patients with dedifferentiated (DD) liposarcoma (LPS), did not meet its primary endpoint of progression free survival ...

For information, the company have announced that the Brightline-1 trial investigating Brigimadlin in dedifferentiated liposarcoma did not meet its primary endpoint and they will no longer be pursuing ...

According to interim results from the phase 2 SARC-028 trial, Keytruda (pembrolizumab) reduced tumor size for 33 percent of patients with undifferentiated pleomorphic sarcoma and dedifferentiated ...