Patients with arthritis and vascular disease may receive both low-dose aspirin and other nonsteroidal antiinflammatory drugs. We therefore investigated potential interactions between aspirin and ...

However, whereas NSAIDs inhibit the two recognized forms of the enzyme, also referred to as cyclooxygenase-1 and cyclooxygenase-2, the coxibs are selective inhibitors of cyclooxygenase-2.

Purpose: A summary of the basic science underlying the current controversies regarding cyclooxygenase-2 (COX-2)-selective nonsteroidal antiinflammatory drugs (NSAIDs), including data on their ...

Occult Metastases in Lymph Nodes Predict Survival in Resectable Non–Small-Cell Lung Cancer: Report of the ACOSOG Z0040 Trial We designed a phase III study to test the hypothesis of whether celecoxib ...

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. However, research on COX-2 regulation of ferroptosis ...

Fig 1. CALGB 30801 CONSORT diagram. COX-2, cyclooxygenase-2; CIDI, Composite International Diagnostic Interview; ECOG, Eastern Cooperative Oncology Group; PE, pulmonary embolism. (*) Not eligible for ...

Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance. Cancer Immunology Research , 2017; DOI: 10.1158/2326-6066.CIR-16-0400 Cite This ...

Using selective cyclooxygenase 2 inhibitors in people with previous severe allergic reactions to non-selective non-steroidal anti-inflammatory drugs:- Should all patients who have experienced a severe ...

Cyclooxygenase-Inhibitoren sind als Antirheumatika und Analgetika schon lange in Gebrauch. Nun könnten die Wirkstoffe in einen ganz anderen Bereich vordringen: die Prävention und Therapie von Krebs.