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Rheumatology and Immunology Research (RIR)是中国国家皮肤与免疫疾病临床医学研究中心的官方期刊,立足全球,放眼中国及亚太地区发表风湿病学与免疫学领域的科研成果。
These clinical features, along with knowledge of the relationship between autoimmunity and immunodeficiency, might be useful for differential diagnosis and lead to an increase in well-defined ...
Aly et al. [17] provided evidence that risk for islet autoimmunity drastically increased in DR3/4-DQ2/DQ8 siblings who shared both HLA haplotypes identical by descent with their diabetic proband ...
Immunotherapy for advanced melanoma induces serologic and clinical manifestations of autoimmunity. We assessed the prognostic significance of autoimmunity in patients with stage IIB, IIC ...
The finding that immune recognition of cancer is directed against self antigens raises the issue of how physiological mechanisms that maintain immune tolerance to self (to prevent autoimmunity) also ...
The odds are greater if you are a woman, you have a genetic predisposition to autoimmunity, or you are exposed to certain pollutants. These diseases include more than 100 lifelong and costly ...
Tolerance is the process that eliminates or neutralizes such autoreactive cells, and a breakdown in the working of this system can cause autoimmunity. Immature T cells migrate to the thymus ...
In healthy mice in the absence of infection, this change did not trigger autoimmunity to the prostate. When the researchers infected mice with a bacterium that expressed the prostate self-peptide ...
Louis, Stanford University School of Medicine and Oxford University has developed a way to find crucial protein fragments that drive autoimmunity, as well as the immune cells that respond to them.
"Our findings demonstrate that T cells discriminate self- and neoself-antigens and do not recognize neoself-antigens as self antigens, thus leading to the development of autoimmunity when neoself ...
The common consensus for some time has been that the prevalence of autoimmunity and autoimmune diseases has been on the rise. Decidedly less common, however, is a widely accepted explanation of ...