Using structure-based design, we generated a new semisynthetic series of spectinomycin analogs with selective ribosomal inhibition and excellent narrow-spectrum antitubercular activity.

The development of drug-resistant M. tuberculosis strains has also made treating tuberculosis more challenging. Researchers have been actively looking for novel antitubercular medications with little ...

The Food and Drug Administration (FDA) approved a group of medications called antitubercular medications for the treatment of TB. They are also suitable for the treatment of miliary TB.