Spatial transcriptomics on human brains parsed microglial reactions to amyloid immunotherapy. Both a vaccine and a therapeutic antibody summoned these cells to plaques. Responders expressed TREM2, ...

New research suggests enhancing the brain’s own immune cells could help clear plaques associated with Alzheimer’s disease.

For decades, scientists have focused on amyloid plaques—abnormal clumps of misfolded proteins that accumulate between neurons ...

“Matthew really opened up a new form of epigenetic inheritance,” says Dr. Brent Derry, Eroglu’s supervisor. “He found that amyloids can be inherited, marking a significant discovery in protein-based ...

A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer's disease is underway at UTHealth Houston. In Alzheimer's disease, deposits of beta-amyloid and ...

Scientists have long been racking their brains for ways to treat Alzheimer’s disease, the most common type of dementia.

Northwestern researchers made progress on new biochemical possibilities this week, in both the human brain and everyday ...

But in just the past year and a half, two anti-amyloid drugs—lecanemab (Leqembi) and donanemab (Kisunla)—that can slow the progression of early Alzheimer’s disease have been approved in the US.

Transthyretin Amyloid Cardiomyopathy Treatment Market is estimated to be valued at US$ 1.69 Bn in 2023, and is expected to exhibit a CAGR of 31.1% by 2030. Mr. Shah Coherent Market Insights Pvt. Ltd.

A new study suggests a promising alternative to previous attempts to remove the sticky, toxic amyloid beta plaques from brains with Alzheimer's Disease: enhancing the brain's own immune cells to clear ...